![]() Platinum containing doublet therapy either intravenously or intraperitoneally (usually paclitaxel) for 6 cycles has been the standard of care for many years 5. Debulking surgery can be sandwiched with neoadjuvant chemotherapy or chemotherapy can be administered following primary debulking surgery. Optimal debulking is defined as the largest residual tumor nodule measuring less than 1cm, while suboptimal debulking is when residual tumor is greater than 1cm 5. The goal of surgical debulking is to leave the patient with no visible sites of disease therefore, guidelines for optimal debulking have been adopted. Multiple studies have shown a relationship between the amount of residual tumor following debulking surgery and response rates 4. Ovarian cancer usually metastasizes first within the peritoneal cavity, and surgical debulking informs staging and adjuvant therapy. Frontline treatment for advanced ovarian cancer consists of surgery in conjunction with chemotherapy.
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